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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
AKAP8L
All Species:
22.42
Human Site:
Y435
Identified Species:
54.81
UniProt:
Q9ULX6
Number Species:
9
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q9ULX6
NP_055186.2
646
71640
Y435
T
A
D
F
L
Q
E
Y
V
T
N
K
T
K
K
Chimpanzee
Pan troglodytes
XP_512453
670
74401
N459
T
A
D
F
L
Q
T
N
L
K
N
K
T
K
Q
Rhesus Macaque
Macaca mulatta
XP_001113053
736
80624
Y530
T
A
D
F
L
Q
E
Y
V
T
N
K
T
K
K
Dog
Lupus familis
XP_853021
648
71770
Y434
T
A
D
F
L
Q
E
Y
V
A
N
K
T
K
K
Cat
Felis silvestris
Mouse
Mus musculus
Q9R0L7
642
71435
Y436
T
A
D
F
L
Q
E
Y
V
T
N
K
T
K
K
Rat
Rattus norvegicus
Q63014
687
76143
Y434
T
V
E
F
L
Q
E
Y
I
I
N
R
N
K
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001505595
296
33832
L163
E
H
N
R
N
R
R
L
M
M
D
Q
S
K
K
Chicken
Gallus gallus
Q5ZJ02
565
63393
T420
T
A
M
R
K
Q
Q
T
S
N
Q
T
E
N
A
Frog
Xenopus laevis
NP_001091313
494
55916
T362
D
H
M
M
K
V
E
T
V
H
C
S
A
C
S
Zebra Danio
Brachydanio rerio
NP_998384
645
69460
Y416
T
T
D
F
L
Q
E
Y
L
N
N
K
Y
K
K
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
87.1
86.4
92.5
N.A.
92.5
34.3
N.A.
29.1
23.3
24.7
35.7
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
89.4
86.5
95.5
N.A.
94.2
50.2
N.A.
32.9
40
40.7
52
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
66.6
100
93.3
N.A.
100
60
N.A.
13.3
20
13.3
73.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
80
100
93.3
N.A.
100
80
N.A.
53.3
26.6
13.3
80
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
60
0
0
0
0
0
0
0
10
0
0
10
0
10
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
10
0
0
10
0
% C
% Asp:
10
0
60
0
0
0
0
0
0
0
10
0
0
0
0
% D
% Glu:
10
0
10
0
0
0
70
0
0
0
0
0
10
0
0
% E
% Phe:
0
0
0
70
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
20
0
0
0
0
0
0
0
10
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
0
0
0
10
10
0
0
0
0
0
% I
% Lys:
0
0
0
0
20
0
0
0
0
10
0
60
0
80
70
% K
% Leu:
0
0
0
0
70
0
0
10
20
0
0
0
0
0
0
% L
% Met:
0
0
20
10
0
0
0
0
10
10
0
0
0
0
0
% M
% Asn:
0
0
10
0
10
0
0
10
0
20
70
0
10
10
0
% N
% Pro:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% P
% Gln:
0
0
0
0
0
80
10
0
0
0
10
10
0
0
10
% Q
% Arg:
0
0
0
20
0
10
10
0
0
0
0
10
0
0
0
% R
% Ser:
0
0
0
0
0
0
0
0
10
0
0
10
10
0
10
% S
% Thr:
80
10
0
0
0
0
10
20
0
30
0
10
50
0
0
% T
% Val:
0
10
0
0
0
10
0
0
50
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
60
0
0
0
0
10
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _